Synthesis of LW223 precursor
The development, manufacture, and supply of 1 gram of (R)-(N-sec-Butyl)-3-chloromethyl-N-methyl-4-phenylquinoline-2- carboxamide (i.e. [18F]LW223 precursor) alliquoted as 250 x 4 mg as well as 50 mg of (R)-N-(sec-butyl)-3-(fluoromethyl)-N-methyl-4-phenylquinoline-2-carboxamide (i.e. [18F]LW223 standard) for use in clinical trials.
Buyer
The University of Edinburgh
Value
£51,316
Published
5 Sept 2022
Closes
5 Sept 2022
Procurement details
Source
Pcs
Region
UKM75
Procurement method
Limited
Category
Goods
Contract starts
Not provided
Contract ends
Not provided
CPV classifications
33124210
Radiodiagnostic supplies
33124000
Diagnostics and radiodiagnostic devices and supplies
Lots
Lot 1 Synthesis of LW223 precursor
£51,316
Manufacture of a precursor in accordance with GMP standards for APIs for use in clinical trials. The precursor will match set specifications. Racemic LW223 precursor (research grade) will be synthesized and used as impurity standard for chiral HPLC of the GMP precursor. LW223 standard material will be manufactured as research grade product. Re-test data, qua...
Delivery: UKM75
Documents
Unlock document linkSynthesis of LW223 precursor
Not provided
The development, manufacture, and supply of 1 gram of (R)-(N-sec-Butyl)-3-chloromethyl-N-methyl-4-phenylquinoline-2- carboxamide (i.e. [18F]LW223 precursor) alliquoted as 250 x 4 mg as well as 50 mg of (R)-N-(sec-butyl)-3-(fluoromethyl)-N-m...
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