UK Research and Innovation - Oligonucleotide Synthesis and Nucleic Acid Sequencing Services Framework

73000000

Research and development services and related consultancy services

73110000

Research services

24956000

Peptones and protein substances

UKRI wish to put in place a Framework for the purchase of a range of user selectable DNA Sequencing services (Sanger/ ~800-1000 base pair read) from a range of samples and formats including tubes, microtiter plates, preparation & extractions services including from colonies and tissue, with the capability of sequencing from High GC and AT samples.

Delivery: United Kingdom

UKRI wish to put in place a Framework for the purchase of a user selectable range of Custom Gene Synthesis. It is anticipated that this will be divided into 4 sub lots: • Sub lot 2.1 - Custom Gene fragment synthesis (sub 2000bp) • Sub lot 2.2 - Custom Gene fragment synthesis (sub 3000bp) • Sub lot 2.3 - Custom Gene synthesis (3001-5000bp) • Sub lot 2.4 - Cus...

Delivery: United Kingdom

UKRI wish to put in place a Framework for the purchase of a user selectable (via supplier engagement) range of advanced DNA services. It is anticipated that this will be divided into 3 sub lots: • Sub-lot 3.1 - Gene Specific DNA Methylation • Sub-lot 3.2 - Global DNA Methylation • Sub-lot 3.3 - Allele quantification A range of additional advanced DNA service...

Delivery: United Kingdom

UKRI wish to put in place a framework for the purchase of a range of custom Oligonucleotide synthesis services including Custom DNA oligo's in tubes, plates and RNA/siRNA, to be user selectable via supplier engagement with a range of purification and modification options. It is anticipated that this will be split into 2 sub lots: • Sub lot 4.1 - synthesis of...

Delivery: United Kingdom

Sub lot 1.1 - First Generation Nucleic Acid sequencing services For the above sub lot, UKRI wish to put in place a framework for the purchase of a range of user selectable Nucleic Acid sequencing (Sanger/ ~800-1000 base pair read) services to be provided. This could include but is not limited to the following: • Provide Phred 20 quality for as many nucleotid...

Delivery: United Kingdom

Sub lot 1.2 - Second Generation Nucleic Acid sequencing services For the above sub lot, UKRI wish to put in place a framework for the purchase of a range of Second Generation sequencing services from a range of samples and formats including tubes, microtiter plates, preparation & extractions services including from colonies and tissue samples. A range of use...

Delivery: United Kingdom

Sub lot 1.3 - Third Generation Nucleic Acid sequencing services For the above Sub Lot, UKRI wish to put in place a framework for the purchase of a range of Third generation sequencing services from a range of samples and formats including tubes, microtiter plates, preparation & extractions services including from colonies and tissue samples utilising novel o...

Delivery: United Kingdom

Sub lot 2.1 - Custom Gene fragment synthesis (sub 2000bp) UKRI wish to put in place a framework for the purchase of a user selectable (via supplier engagement) range of Custom Gene Synthesis (sub 2000bp). For the above sub lot, a range of user selectable additional services should be available (but are not mandatory). This could include but is not limited to...

Delivery: United Kingdom

UKRI wish to put in place a framework for the purchase of a user selectable (via supplier engagement) range of Custom Gene Synthesis (2001 - 3000bp). For the above sub lot, a range of user selectable additional services should be available (but are not mandatory). This could include but is not limited to the following: • Genes produced with additional synthe...

Delivery: United Kingdom

Sub Lot 2.3 - Custom Gene synthesis (3001-5000bp) UKRI wish to put in place a framework for the purchase of a user selectable (via supplier engagement) range of Custom Gene Synthesis (3001 - 5000bp). For the above sub lot, a range of user selectable additional services should be available (but are not mandatory). This could include but is not limited to the...

Delivery: United Kingdom

UKRI wish to put in place a framework for the purchase of a user selectable (via supplier engagement) range of Custom Gene Synthesis (5001 + bp). For the above sub lot, a range of user selectable additional services should be available (but are not mandatory). This could include but is not limited to the following: • Genes produced with additional synthetic...

Delivery: United Kingdom

Sub Lot 3.1 - Gene Specific DNA Methylation UKRI wish to put in place a Framework for the purchase of a range of Gene Specific DNA Methylation services are required to include, but not limited to: o Perform Bisulfite modification. o Perform PCR reactions. o Perform Pyrosequencing analysis.

Delivery: United Kingdom

Sub Lot 3.2 - Global DNA Methylation UKRI wish to put in place a Framework for the purchase of a range of global DNA methylation services are required to include, but not limited to: o LC MS DNA-methylation analysis. o ELISA that enables the direct quantitation of genomic DNA methylation. o PCR based methods e.g.; Alu and LINE1. o Methylation sensitive restr...

Delivery: United Kingdom

Sub Lot 3.3 - Allele quantification UKRI wish to put in place a Framework for the purchase of a range of Allele quantification services are required to include, but not limited to: o SNP detection and quantification. o Assay development for SNP detection and quantification from pooled DNA with a defined 100bp target region in murine DNA. o Validation of the...

Delivery: United Kingdom

Sub Lot 4.1 - Synthesis of DNA oligonucleotides. UKRI wish to put in place a framework for the purchase of a range of custom Oligonucleotide synthesis services including Custom DNA oligo's in tubes, plates and RNA/siRNA, to be user selectable via supplier engagement with a range of purification and modification options. The production of custom user defined...

Delivery: United Kingdom

Sub Lot 4.2 - Synthesis of Custom RNA oligo's (both Single and double stranded RNA oligoes, siRNA) the supply of siRNA Libraries and the production of custom SiRNA Libraries UKRI wish to put in place a framework for the purchase of a range of custom Oligonucleotide synthesis services including Custom DNA oligo's in tubes, plates and RNA/siRNA, to be user sel...

Delivery: United Kingdom