Awarded Contractocds-h6vhtk-032075

OECD 488 transgenic rodent mutation assay (TGRA) using the Big Blue® rat

The conduct of an OECD 488 transgenic rodent mutation assay (TGRA) using the Big Blue® rat using cII mutant selection for the University of Sheffield. Studies will be conducted to GLP, and are based on the following preliminary study design: 1. Breeding of target cohort of 46 Big Blue male rats, with delivery of a target of 44 rats to Charles River Laboratories (CRL) facility, Ashland Ohio, USA. 2. Transfer of HPLC analytical method for dose formulation analysis (DFA) and method transfer summary performed by CRL. 3...

Buyer

UNIVERSITY OF SHEFFIELD

Value

£366,300

Published

27 May 2022

Closes

27 May 2022

Procurement details

Source

Find a Tender

Region

Sheffield

Procurement method

Limited

Category

Services

Contract starts

Not provided

Contract ends

Not provided

CPV classifications

73111000

Research laboratory services

Lots

Lot 1 OECD 488 transgenic rodent mutation assay (TGRA) using the Big Blue® rat

£366,300

In August 2021 the University of Sheffield entered into a contract with WuXi AppTec (Hong Kong) Ltd (Find A Tender Service Contract Award Notice Publication Reference: 2021/S 000-021618) for the provision of IND enabling toxicology study services for M102 (small-molecule drug candidate; oral route, once daily), including 2 animal studies. It is now the inten...

Delivery: Cheshire East

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Contains public sector information licensed under the Open Government Licence v3.0.