Proton range verification detectors

The PRECISE proton therapy research group at the University of Manchester and the Christie NHS Foundation Trust is developing a system to verify range during proton beam therapy treatments. Range uncertainty is arguably one of the biggest challenges in proton therapy. Range uncertainty arises from a number of sources: imaging, dosimetry, stopping powers, however, the largest uncertainty is always the patient. Patient setup, highly heterogeneous tissue, implants, or bone/tissue interfaces as well as anatomical chang...