Provision of whole genome DNA sequencing services for the detection of point mutations

Public Health England (PHE) requires the provision of whole genome DNA sequencing (WGS) services for the detection of point mutations in tissue samples. Due to the nature of the work, any proposed solution must be able to fulfil the following requirements: - The service must include the receipt of sample(s) from PHE, WGS library preparation and sequencing, and delivery of data back to PHE. - The WGS system must be able to detect single mutations in genes that are usually mutated in acute myeloid leukaemia. - The ma...