Laboratory Services for Glymphatic Study

The main aim of this research project is to identify, in a large cohort of PD patients, relationship between the phenotype (in motor, psychiatric, functional and cognitive symptoms, and sleep quality) of cases of sporadic or familial forms of Parkinson's disease and AQP4 SNP genetic variations as genetic modifiers of the function of the glymphatic system. This cross-sectional study aims at recruit up to 800 consecutive patients with PD across three large Centres in southern England. This tender is for the blood sam...