UKSBS RFP PR17177 TIRF Microscope System

The TIRF microscope system covered by this requirement is intended to provide the MRC Laboratory of Molecular Biology in Cambridge with an instrument able to quantitatively image single molecules at high speed in multiple channels simultaneously. The intended applications include in vitro reconstitution of molecular assemblies such as a) motor protein tracking assays and b) the self assembly and dynamics of bacterial cytoskeletal. proteins. Additional applications include live cell TIRF/HILO imaging and PALM/STORM...